Tired of wet underarms staining your shirts or embarrassed by a damp handshake? Excess sweating under the arms, or on the palms or soles can absolutely compromise your ability to work and socialize. If topical prescription strength antiperspirants have failed to work for you, injections with Botox or Dysport may dramatically reduce your sweating in these sensitive areas. Botox and Dysport work by temporarily blocking the chemical signals from the nerves that tell sweat glands to produce sweat. When the glands don’t receive these signals, sweat isn’t produced and your skin stays dry in the targeted areas. Sweat continues normally in untreated regions of the skin. Prior to injections, the skin is numbed and cooled with ice to increase your comfort. Typically, one session of Botox or Dysport injections is needed to achieve results, and sweating gradually returns between 6 and 9 months for most.