A 46-year-old woman came into our office concerned by a growing light tan spot on her cheek. Despite trying topical creams and other light-based treatments elsewhere, the spot continued to darken and grow. After a cosmetic consultation at our Beverly Hills office, we recommended treatment with our PiQo4 picosecond laser. This device targets pigment precisely, which crusts off a few days after treatment. 1 week after a single session, this patient’s brown spot has nearly disappeared. Any remaining pinkness will continue to fade completely. Given her great result, she is now treating brown spots on her arms, hands, and chest.